{"id":31884,"date":"2025-04-08T12:18:46","date_gmt":"2025-04-08T10:18:46","guid":{"rendered":"https:\/\/parkinsonfonds.nl\/?post_type=onderzoek&#038;p=31884"},"modified":"2025-04-08T12:25:24","modified_gmt":"2025-04-08T10:25:24","slug":"nieuw-inzicht-in-celdood-van-dopamine-neuronen-kan-parkinson-onderzoek-vooruithelpen","status":"publish","type":"onderzoek","link":"https:\/\/parkinsonfonds.nl\/en\/onderzoek\/nieuw-inzicht-in-celdood-van-dopamine-neuronen-kan-parkinson-onderzoek-vooruithelpen\/","title":{"rendered":"Nieuw inzicht in celdood van dopamine neuronen kan parkinson onderzoek vooruithelpen"},"content":{"rendered":"<p class=\"attachment\"><a href='https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny.jpg'><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"201\" src=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-300x201.jpg\" class=\"attachment-medium size-medium\" alt=\"\" srcset=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-300x201.jpg 300w, https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-1024x687.jpg 1024w, https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-768x515.jpg 768w, https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-1536x1031.jpg 1536w, https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-2048x1374.jpg 2048w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"31884\" class=\"elementor elementor-31884\" data-elementor-post-type=\"onderzoek\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8e1db1f overview-light hero-header e-flex e-con-boxed e-con e-child\" data-id=\"8e1db1f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-62d94a7 hero-section_holder e-flex e-con-boxed e-con e-child\" data-id=\"62d94a7\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-872d8ad e-flex e-con-boxed e-con e-child\" data-id=\"872d8ad\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d4b5b66 elementor-widget elementor-widget-button\" data-id=\"d4b5b66\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"\/nieuws\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-icon\">\n\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-chevron-left\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M34.52 239.03L228.87 44.69c9.37-9.37 24.57-9.37 33.94 0l22.67 22.67c9.36 9.36 9.37 24.52.04 33.9L131.49 256l154.02 154.75c9.34 9.38 9.32 24.54-.04 33.9l-22.67 22.67c-9.37 9.37-24.57 9.37-33.94 0L34.52 272.97c-9.37-9.37-9.37-24.57 0-33.94z\"><\/path><\/svg>\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Terug naar overzicht<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-84bb33a e-flex e-con-boxed e-con e-child\" data-id=\"84bb33a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b0c693c elementor-widget elementor-widget-heading\" data-id=\"b0c693c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Nieuw inzicht in celdood van dopamine neuronen kan parkinson onderzoek vooruithelpen<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f5226f8 elementor-widget elementor-widget-post-info\" data-id=\"f5226f8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-f7ba8bf elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<span class=\"elementor-post-info__terms-list-item\">Veroudering<\/span>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-8a1d557 elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>8 April 2025<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-de9a1fa e-flex e-con-boxed e-con e-parent\" data-id=\"de9a1fa\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-bec9e1f e-con-full e-flex e-con e-child\" data-id=\"bec9e1f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-aedcb99 elementor-widget elementor-widget-text-editor\" data-id=\"aedcb99\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun MacChromeBold SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\"><strong>Offici\u00eble titel:<\/strong> Het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SpellingErrorHighlight SCXW15625304 BCX0\">ontbreken<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> van Pitx3 <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">leidt<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> tot <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">postnatale<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">afname<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> van dopamine <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">neuronen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">en<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">wordt<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">geassocieerd<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> met <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">een<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">toename<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> van de pro-<\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">celdoodfactor<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">Noxa<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">en<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">gesplitst<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> caspase 3<\/span><\/span><span class=\"LineBreakBlob BlobObject DragDrop SCXW15625304 BCX0\"><span class=\"SCXW15625304 BCX0\">\u00a0<\/span><br class=\"SCXW15625304 BCX0\" \/><\/span><span class=\"TextRun MacChromeBold SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\"><strong>Hoofdonderzoeker<\/strong>:<\/span><\/span><span class=\"TextRun SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\"> Lars P. van der Heide<\/span><\/span><span class=\"LineBreakBlob BlobObject DragDrop SCXW15625304 BCX0\"><span class=\"SCXW15625304 BCX0\">\u00a0<\/span><br class=\"SCXW15625304 BCX0\" \/><\/span><strong><span class=\"TextRun MacChromeBold SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\">Onderzoeksteam:<\/span><\/span><\/strong><span class=\"TextRun SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">Willemieke<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> M. Kouwenhoven, Edward J. Robinson, Daniek Hamberg, Lars von <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW15625304 BCX0\">Oerthel<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\">, Marten P. Smidt<\/span><\/span><span class=\"LineBreakBlob BlobObject DragDrop SCXW15625304 BCX0\"><span class=\"SCXW15625304 BCX0\">\u00a0<\/span><br class=\"SCXW15625304 BCX0\" \/><\/span><strong><span class=\"TextRun MacChromeBold SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\">Instellingen:<\/span><\/span><\/strong><span class=\"TextRun SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\"> Swammerdam Institute for Life Sciences, Molecular Neuroscience Lab, Universiteit van Amsterdam<\/span><\/span><span class=\"LineBreakBlob BlobObject DragDrop SCXW15625304 BCX0\"><span class=\"SCXW15625304 BCX0\">\u00a0<\/span><br class=\"SCXW15625304 BCX0\" \/><\/span><strong><span class=\"TextRun MacChromeBold SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\">Gepubliceerd<\/span><span class=\"NormalTextRun SCXW15625304 BCX0\"> in:<\/span><\/span><\/strong> <a href=\"https:\/\/www.nature.com\/articles\/s41419-025-07552-w\" target=\"_blank\" rel=\"noopener\"><span class=\"TextRun SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\">Cell Death and Disease (Nature Publishing Group)<\/span><\/span><span class=\"TextRun SCXW15625304 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW15625304 BCX0\">, 2025<\/span><\/span><span class=\"EOP SCXW15625304 BCX0\" data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b619c74 e-con-full e-flex e-con e-child\" data-id=\"b619c74\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e510d3a e-flex e-con-boxed e-con e-parent\" data-id=\"e510d3a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-e5155d0 e-con-full e-flex e-con e-child\" data-id=\"e5155d0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c5be318 elementor-widget elementor-widget-heading\" data-id=\"c5be318\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Doel van het onderzoek<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a250cf0 elementor-widget elementor-widget-text-editor\" data-id=\"a250cf0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\">Het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">doel<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> van <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">deze<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">studie<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> was om <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">te<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">begrijpen<\/span> <\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">waarom<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">en<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> hoe dopamine-<\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">producerende<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">hersencellen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">afsterven<\/span><\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\"> in <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">een<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">gebied<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">dat<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> de substantia nigra <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">heet<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\">\u2014<\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">een<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">kerngebied<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">dat<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">aangetast<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> is <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">bij<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> de <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">ziekte<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> van Parkinson. <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">Wetenschappers<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">weten<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> al <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">langer<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">dat<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> het gen <\/span><\/span><span class=\"TextRun MacChromeBold SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\">Pitx3<\/span><\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">belangrijk<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> is <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">voor<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">deze<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">cellen<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\">, maar het was <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">nog<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">niet<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">duidelijk<\/span> <\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">wanneer<\/span><\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\"> de <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">cellen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">afsterven<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">en<\/span> <\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\">wat het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">precies<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">veroorzaakt<\/span><\/span><span class=\"TextRun SCXW59007319 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW59007319 BCX0\">. <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">Deze<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">kennis<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> is <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">essentieel<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\">, want het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">verlies<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> van <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">deze<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">specifieke<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">cellen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">ligt<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">aan<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> de basis <\/span><span class=\"NormalTextRun ContextualSpellingAndGrammarErrorV2Themed SCXW59007319 BCX0\">van<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\"> de <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">bewegingsproblemen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">bij<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">p<\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW59007319 BCX0\">arkinson<\/span><span class=\"NormalTextRun SCXW59007319 BCX0\">.<\/span><\/span><span class=\"EOP SCXW59007319 BCX0\" data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6ffecc1 elementor-widget elementor-widget-heading\" data-id=\"6ffecc1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Onderzoeksdetails <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-961f38b elementor-widget elementor-widget-text-editor\" data-id=\"961f38b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">De onderzoekers gebruikten muizen waarbij het Pitx3-gen was weggehaald en vervangen door een groen oplichtend merkteken (GFP), zodat de dopaminecellen makkelijk zichtbaar waren. Ze bekeken verschillende momenten v\u00f3\u00f3r en n\u00e1 de geboorte. Tot hun verrassing bleek dat de cellen <\/span><i><span data-contrast=\"auto\">niet<\/span><\/i><span data-contrast=\"auto\"> tijdens de zwangerschap stierven, maar pas <\/span><i><span data-contrast=\"auto\">na de geboorte<\/span><\/i><span data-contrast=\"auto\">, rond dag 3.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Toen ze verder zochten naar signalen van celdood, zagen ze een duidelijke toename van <\/span><b><span data-contrast=\"auto\">Noxa<\/span><\/b><span data-contrast=\"auto\">, een stofje dat cellen aanzet tot zelfvernietiging (apoptose). Om dit te testen, plaatsten ze Noxa in dopamine-achtige cellen in een kweekbakje. De cellen stierven snel af, wat bewees dat Noxa op zichzelf al dodelijk is. Noxa blijkt ook een beschermend eiwit genaamd <\/span><b><span data-contrast=\"auto\">Mcl1<\/span><\/b><span data-contrast=\"auto\"> te blokkeren\u2014een stof die cellen normaal gesproken in leven houdt.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1c2befc elementor-widget elementor-widget-heading\" data-id=\"1c2befc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Bevindingen <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1b164d2 elementor-widget elementor-widget-text-editor\" data-id=\"1b164d2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span class=\"TextRun SCXW87241330 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW87241330 BCX0\">De <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">belangrijkste<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">ontdekking<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> is <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">dat<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">dopaminecellen<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> in de substantia nigra <\/span><\/span><span class=\"TextRun SCXW87241330 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"><span class=\"NormalTextRun SCXW87241330 BCX0\">pas <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">na<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> de <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">geboorte<\/span><\/span><span class=\"TextRun SCXW87241330 BCX0\" lang=\"EN-US\" xml:lang=\"EN-US\" data-contrast=\"auto\"> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">afsterven<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">als<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> Pitx3 <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">ontbreekt<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\">. Dit <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">blijkt<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">sterk<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">samen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">te<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">hangen<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> met <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">een<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">verhoogde<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">hoeveelheid<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">Noxa<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\">. Zonder Pitx3 <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">worden<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">dopaminecellen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">dus<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">kwetsbaarder<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">en<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">meer<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">geneigd<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> om <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">zichzelf<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">af<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">te<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">breken<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\">. <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">Mogelijk<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">kunnen<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> we in de <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">toekomst<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">afsterven<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> van <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">deze<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">cellen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">tegengaan<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> door <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">Noxa<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">te<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">remmen<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> of Mcl1 <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">te<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">versterken<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\">. Dit <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">zou<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">een<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">totaal<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">nieuwe<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> ingang <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">kunnen<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">zijn<\/span> <span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">voor<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> het <\/span><span class=\"NormalTextRun SpellingErrorV2Themed SCXW87241330 BCX0\">behandelen<\/span><span class=\"NormalTextRun SCXW87241330 BCX0\"> van Parkinson.<\/span><\/span><span class=\"EOP SCXW87241330 BCX0\" data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7d222f1 elementor-widget elementor-widget-heading\" data-id=\"7d222f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Betekenis voor pati\u00ebnten, onderzoekers en financiers<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b31ede4 elementor-widget elementor-widget-text-editor\" data-id=\"b31ede4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><span data-contrast=\"auto\">Voor onderzoekers geeft deze studie nieuwe inzichten in de kettingreactie die leidt tot het verlies van dopaminecellen. Het legt een duidelijke link tussen een ontwikkelingsgen (Pitx3) en een zelfmoord-eiwit (Noxa), wat een concreet aanknopingspunt biedt om verder te onderzoeken in menselijke hersenen. Voor pati\u00ebnten en hun naasten betekent dit dat wetenschappers dichter bij een manier komen om <\/span><i><span data-contrast=\"auto\">het daadwerkelijke celdoodproces te stoppen<\/span><\/i><span data-contrast=\"auto\">, in plaats van alleen de symptomen te bestrijden.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p><p><span data-contrast=\"auto\">Voor financiers zoals Stichting ParkinsonFonds is dit onderzoek een mooi voorbeeld van de kracht van goed gerichte investeringen in fundamenteel onderzoek. Twee onderzoekers (Eddy Robinson en Daniek Hamberg) werden grotendeels gefinancierd via de beurs van SPF, wat het belang onderstreept van dit soort steun bij het mogelijk maken van baanbrekend werk.<\/span><span data-ccp-props=\"{&quot;134233117&quot;:false,&quot;134233118&quot;:false,&quot;335551550&quot;:0,&quot;335551620&quot;:0,&quot;335559738&quot;:240,&quot;335559739&quot;:240}\">\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a7f5ede e-con-full e-flex e-con e-child\" data-id=\"a7f5ede\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e5cd88c e-flex e-con-boxed e-con e-parent\" data-id=\"e5cd88c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-c2a0880 e-flex e-con-boxed e-con e-child\" data-id=\"c2a0880\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f7f655a elementor-widget elementor-widget-heading\" data-id=\"f7f655a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Deel dit artikel<\/h5>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c2351de e-flex e-con-boxed e-con e-child\" data-id=\"c2351de\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-61b74aa elementor-share-buttons--view-icon elementor-share-buttons--skin-flat elementor-share-buttons--color-custom elementor-widget__width-auto elementor-share-buttons--shape-square 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data-format=\"standard\"><div class=\"wpgb-card-wrapper\"><div class=\"wpgb-card-inner\"><div class=\"wpgb-card-media wpgb-scheme-light\"><svg data-ratio style=\"padding-top:58.54%\" viewBox=\"0 0 41 24\" aria-hidden=\"true\"><\/svg><div class=\"wpgb-card-media-thumbnail\"><a href=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/fotoDannyHolthausen.jpeg\" tabindex=\"-1\" class=\"wpgb-handle-lb wpgb-lightbox\" data-type=\"image\" data-rel=\"13\" data-title=\"danny Holthausen en opa\" title=\"Enlarge photo\"><div style=\"background-image:url(https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/fotoDannyHolthausen.jpeg)\"><\/div><noscript><img decoding=\"async\" class=\"wpgb-noscript-img\" src=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/fotoDannyHolthausen.jpeg\" alt=\"\" height=\"419\" width=\"745\"><\/noscript><\/a><\/div><div class=\"wpgb-card-media-content\"><div class=\"wpgb-card-media-content-bottom\"><\/div><\/div><\/div><div class=\"wpgb-card-content wpgb-scheme-dark\"><div class=\"wpgb-card-body\"><time class=\"wpgb-block-4 date-text font-label\" datetime=\"2026-05-28T15:45:51+02:00\">28 May 2026<\/time><h3 class=\"wpgb-block-1\">Van elfstedentocht tot hele marathon: Danny fietst en loopt voor zijn vader met parkinson<\/h3><p class=\"wpgb-block-2\">Danny (27) fietste de Elfstedentocht \u00e9n loopt de hele marathon van Groningen \u2014 voor zijn...<\/p><\/div><div class=\"wpgb-card-footer\"><a class=\"wpgb-block-6 highlight-button wpgb-idle-scheme-1 wpgb-hover-accent-1\" href=\"https:\/\/parkinsonfonds.nl\/en\/nieuws\/van-elfstedentocht-tot-hele-marathon-danny-fietst-en-loopt-voor-zijn-vader-met-parkinson\/\">Lees meer <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/10\/arrow-right-white.svg\"><\/a><\/div><\/div><\/div><\/div><\/article><article class=\"wpgb-card wpgb-card-6 wpgb-post-38099\" data-col=\"1\" data-row=\"1\" data-format=\"standard\"><div class=\"wpgb-card-wrapper\"><div class=\"wpgb-card-inner\"><div class=\"wpgb-card-media wpgb-scheme-light\"><svg data-ratio style=\"padding-top:58.54%\" viewBox=\"0 0 41 24\" aria-hidden=\"true\"><\/svg><div class=\"wpgb-card-media-thumbnail\"><a href=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/B25A9943-scaled.jpg\" tabindex=\"-1\" class=\"wpgb-handle-lb wpgb-lightbox\" data-type=\"image\" data-rel=\"13\" data-title=\"Jazz van Kasteren\" title=\"Enlarge photo\"><div style=\"background-image:url(https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/B25A9943-768x512.jpg)\"><\/div><noscript><img decoding=\"async\" class=\"wpgb-noscript-img\" src=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/B25A9943-768x512.jpg\" alt=\"\" height=\"512\" width=\"768\"><\/noscript><\/a><\/div><div class=\"wpgb-card-media-content\"><div class=\"wpgb-card-media-content-bottom\"><\/div><\/div><\/div><div class=\"wpgb-card-content wpgb-scheme-dark\"><div class=\"wpgb-card-body\"><time class=\"wpgb-block-4 date-text font-label\" datetime=\"2026-05-27T15:08:23+02:00\">27 May 2026<\/time><h3 class=\"wpgb-block-1\">Voor zijn opa met parkinson doet Jazz iets wat hij een jaar geleden nog nooit had gedaan<\/h3><p class=\"wpgb-block-2\">Jazz (22) leert zichzelf zwemmen en traint 10x per week \u2014 voor zijn opa, die...<\/p><\/div><div class=\"wpgb-card-footer\"><a class=\"wpgb-block-6 highlight-button wpgb-idle-scheme-1 wpgb-hover-accent-1\" href=\"https:\/\/parkinsonfonds.nl\/en\/nieuws\/voor-zijn-opa-met-parkinson-doet-jazz-iets-wat-hij-een-jaar-geleden-nog-nooit-had-gedaan\/\">Lees meer <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/10\/arrow-right-white.svg\"><\/a><\/div><\/div><\/div><\/div><\/article><article class=\"wpgb-card wpgb-card-6 wpgb-post-38004\" data-col=\"1\" data-row=\"1\" data-format=\"standard\"><div class=\"wpgb-card-wrapper\"><div class=\"wpgb-card-inner\"><div class=\"wpgb-card-media wpgb-scheme-light\"><svg data-ratio style=\"padding-top:58.54%\" viewBox=\"0 0 41 24\" aria-hidden=\"true\"><\/svg><div class=\"wpgb-card-media-thumbnail\"><a href=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny.jpg\" tabindex=\"-1\" class=\"wpgb-handle-lb wpgb-lightbox\" data-type=\"image\" data-rel=\"13\" data-title=\"foto bierbrouwers hans en danny\" title=\"Enlarge photo\"><div style=\"background-image:url(https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-768x515.jpg)\"><\/div><noscript><img loading=\"lazy\" decoding=\"async\" class=\"wpgb-noscript-img\" src=\"https:\/\/parkinsonfonds.nl\/wp-content\/uploads\/2026\/05\/foto-bierbrouwers-hans-en-danny-768x515.jpg\" alt=\"\" height=\"515\" width=\"768\"><\/noscript><\/a><\/div><div class=\"wpgb-card-media-content\"><div class=\"wpgb-card-media-content-bottom\"><\/div><\/div><\/div><div class=\"wpgb-card-content wpgb-scheme-dark\"><div class=\"wpgb-card-body\"><time class=\"wpgb-block-4 date-text font-label\" datetime=\"2026-05-27T10:03:23+02:00\">27 May 2026<\/time><h3 class=\"wpgb-block-1\">Trappend richting Rome: vriendschap, bier en een missie tegen parkinson<\/h3><p class=\"wpgb-block-2\">Twee vrienden fietsen ruim 2200 kilometer van Nederland naar Rome voor het ParkinsonFonds. Ontdek hun...<\/p><\/div><div class=\"wpgb-card-footer\"><a class=\"wpgb-block-6 highlight-button wpgb-idle-scheme-1 wpgb-hover-accent-1\" href=\"https:\/\/parkinsonfonds.nl\/en\/nieuws\/trappend-richting-rome-vriendschap-bier-en-een-missie-tegen-parkinson\/\">Lees meer <img decoding=\"async\" src=\"\/wp-content\/uploads\/2023\/10\/arrow-right-white.svg\"><\/a><\/div><\/div><\/div><\/div><\/article>\t\t<\/div>\n\t<\/div>\n\t<\/div>\n\t<\/div>\n\t\t<\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Wetenschappers weten al langer dat het gen Pitx3 belangrijk is voor dopamine neuronen, maar het was nog niet duidelijk wanneer de cellen afsterven en wat het precies veroorzaakt. Deze kennis is essentieel, want het verlies van deze specifieke cellen ligt aan de basis van de bewegingsproblemen bij parkinson. <\/p>\n","protected":false},"featured_media":31891,"parent":0,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"soort-onderzoek":[43],"class_list":["post-31884","onderzoek","type-onderzoek","status-publish","has-post-thumbnail","hentry","soort-onderzoek-veroudering"],"acf":[],"_links":{"self":[{"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/onderzoek\/31884","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/onderzoek"}],"about":[{"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/types\/onderzoek"}],"version-history":[{"count":4,"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/onderzoek\/31884\/revisions"}],"predecessor-version":[{"id":31897,"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/onderzoek\/31884\/revisions\/31897"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/media\/31891"}],"wp:attachment":[{"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/media?parent=31884"}],"wp:term":[{"taxonomy":"soort-onderzoek","embeddable":true,"href":"https:\/\/parkinsonfonds.nl\/en\/wp-json\/wp\/v2\/soort-onderzoek?post=31884"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}