Multiple System Atrophy (MSA): MSA-P and MSA-C
MSA stands for Multiple System Atrophy. In some ways, this condition can resemble Parkinson’s, but it is not the same. We are including it here because people are sometimes diagnosed with MSA after initially receiving a Parkinson’s diagnosis.
MSA is a rare brain disorder (1,500 to 2,000 people in the Netherlands are affected). In MSA, brain cells gradually die off. This is caused by a build-up of proteins in the nerve cells. MSA usually begins in middle age and does not show a preference for one gender over another.
There are two types of MSA: MSA-P and MSA-C.
MSA-P resembles Parkinson’s, but the progression is faster. It is also characterised by a stooped posture, wheezing when breathing, and frequent loss of balance.
MSA-C often makes a person appear as if they are drunk — they walk unsteadily, have poor hand coordination, and their speech can be difficult to understand. In MSA-C, there is shrinkage of the cerebellum, brainstem, and the small brain (cerebellum).
More characteristics of MSA:
- Movement is difficult; people lose their balance easily and are slow and stiff
- Low blood pressure, which can cause dizziness or fainting
- Sleep problems
- Constipation
- Difficulty with swallowing and speaking
- Urinary problems
- Erectile dysfunction / difficulty with vaginal lubrication
